The level of myeloperoxidase was found to be significantly higher in both adult males and females vs. Chronic brain inflammation was found in male and female offspring mice compared to controls, as assessed at PNDs 1, 21, and 100. ![]() Immobility behavior of offspring was assessed in adulthood (i.e., at PNDs 95-100), using the tail suspension and forced swimming tests. Plasma myeloperoxidase and corticosterone levels were evaluated at PND 100. Brain inflammatory markers including cytokines were assessed in offspring mice on the day of birth (i.e., on the postnatal day-PND 1), upon weaning (PND 21) and at adulthood (PND 100). The effects of maternal standard diet ( laboratory food) were compared to the same diet enriched with low, intermediate, or highly polluted eels. We investigated the impact of perinatal exposure to polluted eels on neonatal, postnatal, and adult brain inflammation, and on the resignation behavior of male and female adult offspring mice. ![]() Several lines of evidence indicate that early-life inflammation may predispose to mental illness, including depression, in later-life. ![]() Soualeh, Nidhal Dridi, Imen Eppe, Gauthier Némos, Christophe Soulimani, Rachid Bouayed, Jaouad Perinatal programming of depressive-like behavior by inflammation in adult offspring mice whose mothers were fed polluted eels: Gender selective effects.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |